Jim Hugunin, IronPython’s creator and now a Microsoft employee discussed and demonstrated IronPython on MSDN TV.
IronPython is an implementation of the Python language on the .NET Framework.
Jim Hugunin gave the presentation on using Python in a Microsoft Windows environment, creating .NET classes, interactive exploration and GUI building from a command prompt and simple embedding as a scripting language in an existing Windows Presentation Foundation application.
The presentation is worth viewing, You can download videos from MSDN website.
IronPython: Python on the .NET Framework